Tuesday, April 29, 2008
Lupus nephritis and prognosis of the factors relevant »
So far, the prognosis of lupus nephritis and ethnic origin, gender and age have not yet found a clear relationship. Most scholars believe that the large number of proteinuria with nephritis syndrome, high blood pressure, treatment has increased serum creatinine poor prognosis. Pathological changes and the prognosis is most closely connected, the type and type Ⅱ generally do not develop end-stage renal disease; Ⅲ of disease activity can have development, but the response to treatment, and 5-year survival rate up to 75.8%; Ⅳ multi-condition Critical, but if timely and correct treatment of 5-year survival rate of 80%, 10-year survival rate 60%; Ⅴ-proliferation is not clear when the prognosis with the same primary membranous nephropathy, but with clear or obvious The proliferative lesions prognosis is poor, and similar type Ⅳ.
Purpura nephritis symptoms
Purpura nephritis symptoms: ① kidney, performance: in half of the patients prior to the onset of one to three weeks with upper respiratory tract infection, almost all cases have characteristics of the symmetry of hemorrhagic rash, urticaria at the beginning of the kind, and then into the skin for high-purple spots Dian, more common in the lower limbs stretch side and buttocks, rash can be repeated within a few months. 60% of the patients have abdominal pain, blood in the stool; about 30% of patients on pain, especially knee and the ankle joint. Some cases of kidney damage in the first rash. Adult gastrointestinal symptoms such as systemic performance may not obvious. ② kidney damage performance: About 40 percent of patients with glomerular damage, more than eight weeks after Purpura there. But may also occur in 2 years later, even before the rash. Henoch-Schonlein purpura kidney damage characterized by hematuria, with mild proteinuria. Clinical performance can be as follows: ① acute nephritis syndrome: accounting for about 30%. ② radical nephritis syndrome: rare. In a few weeks to several months to progress uremia. ③ asymptomatic hematuria and (or) proteinuria syndrome: about 50% of the disease. ④ nephrotic syndrome: about 10% of adults, children see more. ⑤ some patients can develop chronic nephritis syndrome.
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