The differential diagnosis of scleroderma

Connective tissue disease involving the gastrointestinal tract have scleroderma, systemic lupus erythematosus, nodular more arteritis, dermatomyositis, such as rheumatoid arthritis, scleroderma to the most prominent. This article introduces scleroderma caused the differential diagnosis. A) limitations to be scleroderma and all of the following identification. 1. Grouper shrinking early damage to large and small, with skin color or Qing Baise, Weiao or uplift, surface appearance, not inconsistent with the hardware. 2. Atrophic lesions hardening of the moss to light purple shiny flat papules, large and small, often gathered distribution, but not each other integration, the surface of hair follicles horny bolt and sometimes blisters, a skin gradually shrinking. (B) systemic sclerosis and takes all of the following identification. 1. Swelling of adult hard: more from the head and neck skin lesions began to Shoulder of the development of deep dermis swelling and stiffness. Local non-pigmentation, hair loss or shrinkage and performance, self-healing tendencies. 2. Mixed connective tissue disease: patients with systemic lupus erythematosus, scleroderma, and polymyositis dermatomyositis or disease, such as the mixed performance, including Raynaud's phenomenon, the face, swelling of the hands of non-depression, with sausage fingers - Swelling, fever, non-destructive and more arthritis, muscle pain or symptoms of myasthenia gravis. Leaching of nuclear antigen (ENA) and the RNP can be a high antibody titers positive.