Thursday, February 28, 2008

Systemic lupus erythematosus mucosa of the characteristics of the skin

In 75% -80% of the patients in a skin performance, After the joint disease. In 25% of patients, skin diseases into first clinical manifestation. In more general skin lesions at the onset, but a small number of patients can occur in other systems disease a few years later. Systemic lupus erythematosus skin damage varied, mixed. Cheek erythema for the first performance, can be a clinical manifestation in the previous few months or a few years. A sudden rash, initially in cheek, for the small size of the soy bean to edema of light red, bright red or purple spots, increasing year by year expanded to bridge of the nose, when the bridge of the nose and cheek rash bilateral linked, seemed to butterflies, it said erythema of the butterfly. Some patients cheek irregular shape of erythema, skin rash clearly some edge, some not, some rash can be accompanied by surface erosion, exudative,crust formation; some patients rash edema serious. Cheek erythema sustainable few hours, a few days or a few weeks, usually easily repeated. Rash usually can be dissipated without leaving traces, but also in a position pigmented skin rash or varying degrees of telangiectasia, less contraction phenomenon. Some patients with systemic lupus erythematosus, there will be the discoid erythema, in more exposed parts such as the face, neck, ears, arms and chest before, or a bulk distribution patchy distribution. It also can occur red, papules, telangiectasia, there can be a separate one of the lesions can also occur several simultaneously or successively, the body parts are involved. Systemic lupus erythematosus patients have alopecia, in the forehead on the often short, broken hair, known as lupus hair, and there alopecia areata, thin hair. About 20% of patients have vasculitis, expressed as means (toe) had a small infarction sharp, can cause ulcers or gangrene, and the end of finger nail skin erythema around. 1 / 5 patients with Raynaud's phenomenon. Activities period, there will be painless ulcer, found in oral mucosa, teeth, hard palate, soft palate, a similar ulcer also occasionally in the nasal septum and vagina.

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