Henoch-Schonlein Purpura clinical manifestations

More urgency incidence, in addition to fever, loss of appetite, nausea, vomiting, and other symptoms in general, the performance of the major skin purpura, gastrointestinal symptoms, joint pain and urinary symptoms. Different situation from time to onset cases the same, to see most skin purpura, a separate, also at the same time or in succession with joints, gastrointestinal or urinary tract symptoms.
First, the onset of skin purpura often the first performance Purpura size, the higher the skin surface, was fuchsia, the pressure does not fade, can be integrated into films, or a herpes-like, shape or kind urticaria erythema, and edema associated with nerve.
Even when serious ulcers and necrosis can occur. Purpura was particularly prevalent in the extremities and buttocks extending side, ankle and lower extremities, such as the knee joint, the more obvious that there was symmetry in batches easily repeated attack.
Second, many children have gastrointestinal symptoms including abdominal pain, the more intense paroxysmal of colic, or Duntong to Qizhou or significantly lower abdomen, tenderness, but no muscle tension. Can be accompanied by diarrhea and hematochezia varying severity, a tar-like stool or bright red. There are also severe vomiting, but hematemesis rare. Such as abdominal pain, blood in the stool before seen in the skin purpura, with the identification of acute abdomen. The disease can intestine submucosal edema and hemorrhage, leading to intestinal dysfunction, and even induced intestinal Invagination.
Third, some children with symptoms of joint pain and swelling of the festival, involving more large joints, such as the knee, ankle, wrist, elbow, not small joint involvement. Can be single, multiple or submission migrans. Joint swelling, pain, pain when aggravated, accompanied local micro heat, heavy flu have heartburn. Joint symptoms subsided after no sequelae.
4, urinary symptoms due to urinary tract mucosa capillary permeability increase, there may be hematuria and microalbuminuria, with purpura seen disappear. However, in children with Henoch-Schonlein purpura about 1 / 3 to 1 / 2 of kidney involvement, saying Purpura Nephritis. The pathological changes of kidney determine prognosis. Urine acute phase change more than 2 to 3 weeks there, but also appeared in the rear Purpura dissipated.
Most patients showed a small amount of urine protein and red blood cells under the microscope, and sometimes see a type may appear gross hematuria. Generally good prognosis, even with a rapidly progressive glomerulonephritis, and for the development of acute renal failure, poor prognosis. Part of a large number of children with proteinuria, hematuria, edema, hypertension, hypoproteinemia and hypercholesterolemia as the nephrotic syndrome. Hematuria and proteinuria sustainable few months or few years, most of the last still fully recovered. There are very few children with varying degrees of renal damage after a chronic glomerulonephritis, eventually developed chronic renal failure.
Fifth, other symptoms occasionally cerebral hemorrhage, or a convulsion, temporary paralysis, aphasia, severe cases can cause death. Others such as nosebleeds, bleeding gums, muscle hemorrhage, or bleeding testicular swelling Pulmonary Hemosiderosis, are extremely rare.