Pediatric Clinical manifestations of rheumatoid

Can occur at any age, but 2 to 4 years and 8 to 10 years of age incidence maximum. Women more than men. Disease can be divided into three types: A generalized type more common in young children, women and men are infected. Mainly as fever, rash, arthritis and other symptoms of organ involvement. Fever was flip-heat, one day, there may be one or two peaks, high fever up to 40 ℃, daily fluctuations up 3 ~ 4 ℃, shivering with fever before. Febrile illness during the heavier, heat Forward children generally turned for the better. Sustainable fever a few weeks or a few months, often natural ease, but easy to relapse. During the rash accompanied fever, rash was pleomorphic, scattered ranging from the size of erythema, dual-can be integrated into, or a ring erythema, skin rash appeared short, easy to relapse to the trunk most were also seen limbs, or even the palm of your hand and foot. Arthritis symptoms are lighter, more performance for multi-joint involvement, have no joint symptoms. There are children with different degrees of liver, spleen and lymph nodes. There are a small number of cases, pleurisy, pericarditis or myocarditis. Second, multiple joints of this type of performance similar to adult rheumatoid arthritis, started only 1 ~ 2 joint involvement, as early migration of becoming more fixed symmetry arthritis. Major facet of this type of the characteristics of the proximal interphalangeal joint disease most often, followed by the metacarpophalangeal and toe joints, the joints can also be involved if the knee, ankle, wrist, elbow, hip, spine, in particular, such as cervical spine joints . More slow onset of this type, the incidence of intense minorities. In the early partial pain, morning stiffness, after joint swelling, heat, pain, gradually turned into a spindle, activities restricted, knee, elbow, that, the wrist was fixed flexion. Only a small number of cases does not swollen pain without swelling or pain. Muscle cramps near the joints, and then atrophy, deformation end to disease and deformed joints and stiffness, joint deformation was particularly prevalent in six months to one year after the onset, that is, to reduce pain at this time. If other parts of the body such as the joint involvement can cause cervical neck pain and stiffness, temporomandibular joint involvement often caused chewing obstacles. Mild systemic symptoms, only fever, fatigue, decreased appetite, mild anemia, and mild liver, spleen and lymph nodes. Children with a few joints in the vicinity of subcutaneous nodules. For rheumatoid factor positive. Third, single-articular joints involved only a small number (often one), mainly involving large joints such as the knee, ankle, elbow and other places. Joints can be a chronic or recurrent inflammation process, but rarely cause serious joint activities restricted. This type of joint involvement in a small number of cases at the same time or after iridocyclitis can sometimes be the first symptom of this type. Systemic symptoms minor, there are low heat, weakness, mild anemia and liver and spleen enlarged lymph nodes.