Purpura Nephritis children etiology and clinical manifestations

Purpura Nephritis to Henoch-Schonlein purpura caused by secondary kidney damage, is a kind of immunization-related systemic vasculitis involving the kidney from nephritis.
Etiology and Epidemiology: Cause unknown, and may be some bacteria or virus infection, may also be associated with certain drugs or food allergies caused by the elements. More occurred in school-age children
Children, men more than women. Pathological modern medicine: Purpura Nephritis pathological changes varied, and focal segmental lesions of diffuse mesangial proliferative more, or more than 60 percent, with crescent formation. Rabbit epidemic
Pathological to diffuse mesangial IgA Mission District for the massive deposition characteristics, complement C3 deposition in the main, suggesting that activation of complement these lanes are bypass channels. Mesangial electron microscope in the District, that
- Dense deposit, a massive giant nodules.
In the Pathogenesis of Medicine: The etiology of the disease is known as more of intrinsic blood, Exogenous Fengxie or food goods moving wind, wind or heat of the hot drug Chi Cheng Bo, burns blood favorable, thus forcing blood Wang Xing.
Spillover of the skin, gastrointestinal, forcing a great, and renal, and see Nixie. Spleen deficiency of blood or not perturbing gas virtual Huozhuo favorable, the card can also be a Nixie. Tongxinluo kidney damage, water metabolism of loss
Often, that the proliferation of skin edema. Of the disease in renal disease, and the liver and spleen.
Clinical manifestations: 1. Hematuria: performance for the naked eye or microscopic hematuria, and severity ranges, sustained or repeated seizures. Can be associated with varying degrees of proteinuria. 2. Hypertension: about 20% to 40%, blood pressure is generally mild to moderate increase, there may be individual cases of hypertensive encephalopathy. Hypertension often associated with abnormal urine at the same time,
Now, the majority of rapid restoration. 3. Edema: generally mild edema, and was particularly prevalent in the face, for the performance of a few highly edema. Multi-such as nephropathy, or those with renal insufficiency.