Thursday, March 20, 2008

Clinical acute glomerulonephritis performance and inspection

A clinical performance Acute nephritis was particularly prevalent in children, More men than women. Typical symptoms usually in the streptococcus infection after one to three weeks (an average of 10 days or so) onset. The incubation period equivalent to the initial pathogenic antigen produced after immunization induce the immune complexes, the time-respiratory infections, skin infections than the incubation period are short. Rapid onset of this disease, varying severity. edema, hematuria, hypertension, and the whole body fatigue and not to diet, low back pain, dizziness, and so on. Edema a rate of about 80 percent to 90 percent, to light only eyelid edema, can be seriously affected when the body. Hematuria a rate of about 40 percent, urine washing meat water samples, generally no obvious symptoms of urinary tract stimulation, gross hematuria sustained 1 ~ 2 weeks into microscopic hematuria. Higher blood pressure found in 80% cases, generally light or moderate blood pressure increased. Some cases may occur in the acute phase of acute congestive heart failure, hypertensive encephalopathy, acute renal failure and other serious complications. The clinical manifestations of atypical cases can be no edema, hypertension and gross hematuria. Only later, the streptococcal infection and urine routine examination found microscopic hematuria, light, subacute only urine routine and in the C3 abnormal blood. Typical performance of a syndrome of acute nephritis. Second, laboratory and other tests 1, urine examination: RBC urine routine visible, and most deformed red blood cells; proteinuria, 75 percent of patients 24 h urinary protein adequate less than 3.0 g; common tubular epithelial cells, leukocytes, transparent and type of particles, in addition to Visibility RBC tube, showing a bleeding exudative glomerular inflammation is an important feature of acute nephritis. 2, blood routine examination: WBC may increase the normal, mild anemia, as is normal pigment cells anemia, erythrocyte sedimentation rate in the acute stage by fast. 3, renal function and blood tests: the acute phase decline in glomerular filtration rate, the clinical manifestations of a azotemia. Serum potassium, chlorine can be increased slightly, mildly lower serum sodium, plasma protein mild decline. 4, fibrin degradation products (FDP) Determination: blood, urine FDP determination can be positive. 5, immunological tests: (1) Antistreptolysin-O antibody (ASO): The positive rate of 50 percent to 80 percent. Usually streptococcus infection after 2 to 3 weeks there, three to five weeks titer reached the peak, after gradually declining. (2) of B-DNA (anti-DNAse B) and anti-hyaluronidase (anti-HASe): septic ulcer disease caused by the acute nephritis in a higher positive rate, there are more than two times titer increased when suggested that the near future is streptococcus infection.

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