Acute Glomerulonephritis diagnosis and differential diagnosis

Often after a streptococcal infection in ~ 3 weeks in hematuria, proteinuria, edema and hypertension, and other clinical features, such as even oliguria azotemia and acute nephritis comprehensive performance, and with decreased serum total C3 complement decline. Positive urine test urine protein, RBC, WBC, and possession of urine. Disease incidence in eight weeks, gradually reduced to return fully to normal, can be clinically diagnosed as acute nephritis. Symptomatic treatment, if the glomerular filtration rate of decline or disease in 1-2 months are not yet fully improved renal biopsy should be timely, clear diagnosis. First, the acute onset of glomerular nephritis disease syndrome 1, other pathogens infection after acute nephritis many bacteria, viruses and parasites infection can cause acute nephritis. At present more than the more common species such as varicella virus - herpes zoster virus flu or a period of 3-5 days after infection, the virus infected the majority of clinical manifestations of acute nephritis less frequently associated with lower serum complement, rarely edema and hypertension, renal function normal, self-limited clinical process. 2, mesangial glomerulonephritis also known as capillary membrane proliferative glomerulonephritis, in addition to clinical manifestations of acute nephritic syndrome, often with nephrotic syndrome, the tendency to self-healing lesions going. 50% - 70% of the patients with persistent hypocomplementemia, not to resume within eight weeks. 3, mesangial proliferative glomerulonephritis (IgA nephropathy and non-IgA mesangial proliferative glomerulonephritis) of the patients showed precursor infection syndrome of acute nephritis, C3 in patients with normal, non-healing illness tendencies. IgA nephropathy patients with the disease incubation period is short, can be infected after a few hours to a few days a gross hematuria, hematuria can be repeated attack, and some patients with IgA increased. Second, rapidly progressive glomerulonephritis with the onset of acute nephritis similar process, except for acute nephritic syndrome, often early in oliguria, anuria rapid deterioration of renal function characterized. Severe acute nephritis showed acute renal failure and the disease difficult to distinguish should promptly make a clear diagnosis of renal biopsy. Third, systemic disease renal involvement in systemic lupus erythematosus nephritis and Henoch-Schonlein Purpura Nephritis and other acute nephritic syndrome may show, but other systems involved with the typical clinical presentation and laboratory tests, which we can identify. When clinical diagnosis difficult, acute nephritic syndrome patients need to be considered for a clear diagnosis of renal biopsy to guide therapy. The indication for renal biopsy: 1, oliguria week or more, or with a reduced volume of renal function deterioration; 2, the course for more than two months without improvement trend; 3, acute nephritis with nephrotic syndrome, syndrome .