How treatment Henoch-Schonlein Purpura Nephritis how prognosis?

Henoch-Schonlein Purpura Nephritis majority of the patients are children tend to self-limited, mild symptoms, not special treatment. But in the acute phase should pay attention to warm, bed rest, suspended all suspicious allergy drugs and food, to avoid contact with suspicious allergens. If there can be allergy drug of allergy symptoms (such as chlorpheniramine and diphenhydramine, Astemizole, etc.) symptomatic treatment. Other symptomatic treatment, including anti-infection, lower blood pressure and diuretic therapy. Effect of glucocorticoid on joint pain, abdominal pain and gastrointestinal symptoms have some therapeutic effect, the general use of prednisone 1-2 mg kg_1. D_1, can be used 1-2 weeks. Purpura severe skin can be used hydrocortisone or de-de-hydride succinic acid treatment. Generally believed that the damage to the kidney hormone had no significant effect, can not change Henoch-Schonlein Purpura Nephritis course and prognosis, we can not prevent the recurrence of purpura. But for a rapidly progressive glomerulonephritis syndrome onset of Henoch-Schonlein Purpura nephritis patients, consideration should be given timely use of high-dose methylprednisolone therapy, and to anticoagulant therapy and anti-platelet aggregation, about more than half of the patients effective treatment. Some people think that the performance of the nephrotic syndrome patients with Henoch-Schonlein Purpura Nephritis to use hormone therapy, although not of primary nephrotic syndrome, but the swelling and reduce proteinuria or have a certain effect. Poisons such as cells of the therapeutic effect of cyclophosphamide, and so was not sure. Allergic Purple paralysis nephritis Chinese medicine treatment for the Blood Circulation, mainly Qingrejiedu. Henoch-Schonlein Purpura Nephritis efficacy and clinical performance of the type and extent of the pathological changes are closely related. Minor lesions and better efficacy of acute nephritis, chronic glomerulonephritis type less effective; pathological changes to Ⅱ, Ⅲ type of effect is good. And Ⅳ, Ⅴ of poor treatment. Ⅳ pathological changes in the level and above should pay attention to the protection of renal function. Henoch-Schonlein Purpura Nephritis and the prognosis of patients with kidney closely related to the pathological changes. According to incomplete statistics, about 52% of the patients in the onset can complete remission within a year, 15% of sustainable existence gross hematuria and Victoria proteinuria (1_3 g / day), 18% of the patients with microscopic hematuria sustainable existence and microalbuminuria, no decline in glomerular filtration rate, only 5% of patients in the next few years can progress to chronic renal insufficiency. Some of the patients were children 10 years of follow-up, results showed that 70% -80% of the patients can complete remission, 15% of the patients have sustained renal lesions, 8% of the renal failure patients, and only 1% of patients die . , Henoch-Schonlein Purpura Nephritis affect the prognosis of the main factors: ① age: children with a better prognosis, adult-onset patients with poor prognosis; ② clinical performance: performance for the large number of proteinuria and hypertension associated with a poor prognosis; ③ kidney pathological changes: Some of the statistics Ⅳ more than 40% of patients can progress to chronic renal insufficiency, and the following type Ⅲ only 3 per cent of patients can progress to chronic renal insufficiency; is under the skin and endothelial immune complexes Deposition of patients, more immune complex is confined to the mesangial area, the prognosis is poor.