Friday, April 4, 2008

TB in children how to use drug therapy

Children are suffering from TB is of primary pulmonary tuberculosis. Since the disease after 3 to 6 months the majority of lesions or tend sclerosis began absorption, absorption calcification in 2 years and recovered. More than 95 percent of its general clinical course is benign. If conditions deteriorate to the development of more than seen in the first six months after infection, so protracted illness refractory up to 2 to 3 years or longer. Therefore treatment of TB, it is necessary to early treatment and use in the treatment of drug-sensitive and adhere to the completion of adequate treatment. In a high state of the children with allergies to row with the TB bacteria, strict isolation and take strict disinfection measures to avoid duplication of Mycobacterium tuberculosis infection. Desensitization and timely use of calcium and vitamin C to make a lot of adjuvant therapy. If large tracts of real change or pulmonary atelectasis existence or serious poisoning symptoms can be adrenal cortex hormones. Generally believed that no primary infectious tuberculosis, solely on the basis of positive tuberculin tests and X-ray examination was not discovered, children can be life as usual, nursery or school. Only a few symptoms of the conduct of primary tuberculosis, or severe acute tuberculosis patients, the light of the specific situation should be given proper rest and treatment in isolation. Quality anti-TB drugs by the order is divided into A, B, C three categories: A drugs: isoniazid and rifampicin. B drug streptomycin, pyrazinamide, and ethambutol, kanamycin, B sulfur Isonicotinic amines, Cycloserine, purple adriamycin and tendril adriamycin. Class C drugs: sodium p-aminobenzoic acid and ammonia thiourea. By clinical experience has shown that children with tuberculosis chemotherapy good results. According to drug efficacy and toxicity size, the evaluation of the anti-TB drugs are as follows: ① first-class level, isoniazid and rifampicin, two for first-class streptomycin, pyrazinamide, B amine and sulfur Isonicotinic ethambutol. ② second: the amino acid sodium, kanamycin, tendril adriamycin, purple adriamycin and Cycloserine. ③ third class for ammonia thiourea.

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