Garcin's syndrome

Overview said, the side of the skull base syndrome; Garcin - GBS's syndrome. Cause pathogenesis of skull base tumors (sphenoid, temporal bone, intraorbital, middle cranial fossa meningioma. near the petrous bone sarcoma), or from the lower part of the skull of extracranial tumors (maxillary sinus, nasal cavity, nasopharynx cancer) spread to the skull base. to the side of cranial nerves or no damage. Clinical manifestations sexual side of all cranial nerve damage; Lack of substantive brain damage symptoms, and no movement, sensory systems to other brain damage symptoms and signs; lack levy increased intracranial pressure, papilledema and ignore changes in cerebrospinal fluid; Visibility skull film cerebral lesions induced bone destruction. Differential diagnosis (1) middle cranial fossa meningioma (meningioma of middle cranial f ossa) parasellar, superior orbital fissure, petrous apex meningioma known collectively parasellar meningioma, Clinical symptoms and its sudden-bed Butterfly Ridge Meningiomas similar. Petrous apex meningioma patients are mostly middle-aged, often symptom onset to the affected areas of the trigeminal nerve is paresthesia, and the feeling of pain receded, followed by chewing muscles atrophy. Oppression cavernous when there ophthalmoplegia, and eyelid ptosis unilateral exophthalmos; Oppression Eustachian tube is tinnitus and hearing disorders; invasive posterior fossa caused the cerebellopontine angle, cerebellum and brainstem symptoms, have no symptoms of increased intracranial pressure. Middle cranial fossa meningioma lack of lateral focal symptoms. (2) trigeminal neurinomas (erigeminal neurinoma) often side of paroxysmal facial pain pain or numbness of the first symptoms, began to emerge after chewing weakness and atrophy, since tumor development in various directions, there may be different clinical manifestations. Located in the posterior fossa were to VI, VII, VIII cranial nerve symptoms may have advanced cerebellar symptoms, symptoms and increased intracranial pressure after cranial nerve symptoms; in the middle cranial fossa the bottom of the temporal lobe were to visual impairment, oculomotor nerve palsy, exophthalmos. Magic olfactory and epilepsy; Tumors in the saddle, the posterior fossa may cause the opposite of paraparesis, increased intracranial pressure and cerebellar symptoms. X thrum leveled sharp rock films can be seen before the internal bone destruction and the foramen ovale, or hole expansion. (3) nasopharyngeal carcinoma () nasopharyngeal carcinoma of the skull base transfer can produce a series of unilateral neurological symptoms skull base, its clinical manifestations are like the middle cranial fossa or sphenoid ridge meningioma, sometimes with trigeminal neurinomas easily confused. Characterized as nasopharyngeal tumors and extensive skull base. NPC can be no early symptoms, only for the performance of the nasopharynx bilateral and asymmetric side of the pharyngeal recess lighter or disappeared. (4) This syndrome yet with a number of other diseases caused to the majority of cranial nerve palsy identification, such as gray brainstem encephalitis, Yan brainstem disease, such as multiple cranial neuritis. These cranial nerve palsy for more bilateral and there are good features of the disease itself.