Wednesday, March 12, 2008
Guillain-Barre syndrome
Overview also known as acute infection Polyneuritis; Multiple acute nerve root lesions. Acute rose palsy; Landry paralysis. Pathology Disease etiology is not clear so far, most scholars tended to slow HIV infection and autoimmune theory, conjecture infection of peripheral nerve injury to the sheath cells, and the release of the material with antigen, or virus in the peripheral nervous performance of a new antigen. Quadriplegia clinical manifestations of the disease is the most common symptoms first appeared more than two-leg paralysis, upper limb paralysis followed. Quadriplegia or simultaneously. DVT symptoms, reduce muscle tension, the tendon reflexes weakened or disappeared. A subjective sensory dysfunction (numbness, pain and abnormal sensation), the objective sense of light, or a hand Motao like sensory impairments. Muscle tenderness is an important symptom to the gastrocnemius muscle and the one hand, the two bones between muscle obvious. CSF emerging protein-cell separation. About half of the levy patients precursor diseases, the most common are diarrhea and upper respiratory tract infection. Severe cases of respiratory muscle, neck muscle have also paralyzed. 70% of patients had cranial nerve symptoms, the largest ever see facial paralysis, In recent years, glossopharyngeal and vagus nerve First violations arising bulbar paralysis or palsy. Differential diagnosis (1) anterior horn polio (anterior poliomyelitis) ground polio infection caused by an acute infectious disease. Occurred in 10 children below the age, following fever after feeling the absence of obstacles to the flaccid paralysis. Under the anterior horn involvement and the scope of the site, which can be seen in the paralysis of the side limbs, or a single body, physically or both, to a lower limb paralysis styles. CSF protein continued to increase and nasopharyngeal secretions and feces cavity HIV-positive. (2) acute myelitis (acute polimyelitis) of the disease of the nervous system infection by the virus After caused by autoimmune response. Lesions below the level of the campaign, I feel, reflex, in a feel on the edge will have a hypersensitivity, Occasionally constrictions sense of pain and more with bladder, rectum and autonomic dysfunction. Sowing inflammation and the brain stem and brain, there may be psychiatric symptoms, seizures and coma. (3) periodic paralysis (periodic paralysis) as a group for reasons unknown. cyclical attack flaccid paralysis, each include sudden, sustained a few hours to a few days to restore. According to the attack and the change in serum potassium into clinical characteristics of low potassium, potassium and normal hypokalemic three. Unconscious obstacles and sensory impairments. (4) severe myasthenia gravis () is a neuromuscular junction between transmission chronic disorder. The disease characteristics of the involved muscles fatigue very easily, almost every patient had cranial nerve muscle powerless. Symptoms morning light night, and after the break after a marked improvement.
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