Tuesday, March 25, 2008
Commonly used anti-thyroid drugs which several
Antithyroid drugs are commonly used. Thiourea, there are four kinds: ① tapazole; ②-hyperthyroidism; ③ methyl AECA; ④ Propylthiouracil-. Tapazole and hyperthyroidism-drug structure similar to hyperthyroidism-enters the body after taking into tapazole to play a role. Methyl AECA and Propylthiouracil-similar structure of the drug. In the oral drug was rapidly absorbed, about 30-60 minutes blood drug concentration reached a peak. Tapazole plasma half-life of 12 hours for a 6, and 24 hours after the blood concentration of low-or Propylthiouracil-half-life of 2-3 hours. According to the changes in concentration in the blood, in the past many times that they should be served at all, generally eight hours per serving 1. In recent years, he was found in the thyroid tapazole play a role in the sustainable 20-24 hours, so many people stand tapazole daily dosage on the morning of 1 to be served. China used tapazole most, followed by methyl AECA, the other two drugs is rarely applied. Four kinds of drugs each dose is as follows: tapazole, 5 mg per tablet; hyperthyroidism-, 5 mg per tablet; methyl AECA, each tablet 50 mg or 100 mg; Propylthiouracil-per Tablets 50 mg.
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