Henoch-Schonlein Purpura Nephritis What are the causes?

Henoch-Schonlein Purpura Nephritis is Henoch-Schonlein purpura secondary lesions, and Henoch-Schonlein purpura causes have not yet clear, and may be related to infection and allergic reaction. Case before the onset of the infection is the most common upper respiratory tract infection (non-specific or streptococcal infection), such as chlamydia, such as varicella and parasites. There are many cases of drugs (antibiotics, iodine amines, isoniazid, salicylate, barbital and iodide), or food (dairy, fish, prawns, crabs and clams, etc.) allergies. Currently think it is an immune complex disease. In the pathogenesis of IgA play an important role in the acute phase patients was significantly higher serum IgA, IgA can generate affinity between a high molecular weight polymer, and more than 90 percent of cases of skin on the glomerular and vascular wall IgA immunofluorescence positive. Patients with acute phase serum factor VIII activity and low glomerular presence of fibrin (the original), suggesting that coagulation mechanisms involved in the pathogenesis of this disease.