Marchiafave-Bignami's syndrome

Also known as outlined primary corpus callosum degeneration. Cause pathogenesis initially that the disease is caused by the Italian wine corpus callosum demyelination, See also after non-alcoholism caused similar diseases. Possible by the blood-brain barrier and neurological changes in cell membrane permeability changes in the secondary cause. The main clinical manifestations of the sexual performance of dementia and lethargy. Found in drinking heavily middle-aged and older men, was particularly prevalent in the Latino race. General 40-60-year-old onset, 3 ~ 6 years after death, chronic alcoholism performance of the personality changes and dementia. After a dysarthria, ataxia, sphincter obstacles, stroke-like episodes, seizures, apraxia, aphasia and hallucination, paranoia and other neuropsychiatric symptoms. Symptoms often add alternately with ease, quickly emerged last obstacle to death. Differential diagnosis of chronic alcoholism (chroic alcoholism) is a long-term basis drinking heavily the nerve disorder, and the symptoms appeared slow, but lasted longer, and the prognosis is poor. Patients who have a long history of drinking heavily on alcohol dependency and mental (or) physical dependence history. The symptoms of the nervous system is autonomic dysfunction, tremor, peripheral neuritis, seizures, performance of mental disorder with hallucinations, paranoia, tremors state of delirium, personality change, forgotten syndrome and dementia state.