Tuesday, March 25, 2008

Thyrotoxicosis not common types

Symptoms 1, T3 hyperthyroidism Triiodothyronine of hyperthyroidism as T3 hyperthyroidism is that there is no reduction in TBG circumstances, the normal serum T4 or reduced, and a higher serum T3 thyrotoxicosis. Such can be found in Graves disease, multinodular goiter, or high-functioning adenomas. The disease was particularly prevalent in the area of iodine deficiency. Where is the clinical thyrotoxicosis performance, and its normal serum T4 and FT4 or lower, RAIU normal or increased patients of the disease should be suspected. T3 hyperthyroidism about 12% of patients with hyperthyroidism, and the glands may compensate for the smaller and more iodine supply of iodine less T3. In the early stage of hyperthyroidism, antithyroid agents in the treatment and post-treatment relapse see more of it. Diagnosis of this disease: ① have the signs and symptoms of hyperthyroidism; ② serum T4 and FT4 were normal; ③ thyroid iodine uptake rate of 131 normal or increased, not be inhibited by exogenous T3; ④ total serum T3 increased serum ⑤ TBG content normal. The disease is usually treated with the same type of hyperthyroidism, but it should be noted in patients with thyrotoxicosis such symptoms often can not completely disappeared, disable anti-thyroid in the treatment of recurrent easy. Second, T4 hyperthyroidism Most patients with hyperthyroidism, although serum T3 and T4 increased, but the increase of serum T3 concentration degree rather than serum T4. This suggested that the release of more hyperthyroidism, thyroid T3 and T4 peripheral organizations will be transformed into T3 increase. T4 hyperthyroidism means serum T4 has been significantly increased, and normal serum T3 generally characterized by a thyrotoxicosis. T4 hyperthyroidism mainly seen in previous exposure to excessive iodine elderly, the sick or elderly patients, the long-term hospitalization, most were excessive iodine intake so that more synthetic T4 glands. Without excessive iodine intake history can be found, and more tips peripheral tissue T4 into T3 inhibited. T4 treatment of hyperthyroidism in addition to the normal type of hyperthyroidism, the body to appropriately reduce iodine intake.

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