Differential diagnosis of systemic lupus erythematosus

[Differential diagnosis of this disease - with other connective tissue disease, bacterial or viral infections of the disease, histiocytosis X of malignant disease reticuloendothelial cells increased, decreased platelet disease, hemolytic anemia, various types of kidney disease, hepatitis , myocardial - pericarditis, diseases of the nervous system of identification. Particularly with the type of lupus syndrome, neonatal lupus erythematosus syndrome identification. Class lupus syndrome, the most common of which is drug-induced systemic lupus erythematosus. SLE similar to the syndrome that some symptoms, signs, and laboratory test results, and sometimes Nansigoubie. Following some cases help identification: the use of the drug history, and the gender gap not obvious clinical symptoms light, visceral involvement, kidney disease, butterfly erythema, mouth ulcers, hair loss, as well as WBC, thrombocytopenia, hypocomplementemia are rare , anti-Sm and anti-n-DNA (FARR) antibody negative. The main feature is to stop after the clinical symptoms and laboratory signs disappear again when the drug is complex. Sometimes anti-nuclear antibody longer exist, the general prognosis is good. Neonatal lupus erythematosus syndrome of the disease found in infants under six months. Most children with mothers suffering from SLE or other connective tissue diseases, in the RO serum antigen (Sjogren's syndrome A antigen) and La antigen (Sjogren's syndrome B antigens). Health after children have symptoms manifested mainly as a congenital block, lupus-like dermatitis, and self-hemolytic anemia, and in RO La antigen positive. In addition, accompanied congenital heart disease, various defects and endocardial fibroelastosis, WBC and platelet reduction. Lesions as a typical example of the pleadings and Linxie annular erythema, found exposed, which is the head, neck and eyelids, seems to discoid erythema. The disease is self-limited disease, abnormal blood in the more than six weeks of improved lesions may disappear within six months. In addition to children with heart disease, the general prognosis is good. There are reports puberty can be a SLE, the reason is unclear.