Drug-induced lupus diagnosis and treatment of how

Drug-induced lupus is a result of taking certain drugs-induced lupus. So far, known to cause drug-induced lupus drug up to 50 species, such as hydrazine-triazine (hydralazine of triazine), isoniazid, Procaine amide,sulfasalazine, sulfadiazine, Chlorpromazine, methyl dopa, penicillamine, and propranolol (Inderal), oxygen en atenolol (experience Ping), phenytoin, AECA, for the benefit-(reserpine), captopril sulfur acid, tapazole, nitrofurantoin because, allopurinol alcohol, oral contraceptives, penicillin, tetracycline, such as quinidine. And the incidence and total daily dosage of the drug, commonly used drug dose usually a few months later evoked. According to studies, the drug may be changed antigen, the body has its own corresponding antibodies caused. Drug-induced lupus common symptoms of fever, muscle pain, joint pain and pleurisy and pericarditis, but these symptoms are more systemic lupus erythematosus patient's condition light. And cheek rash, oral ulcers, Raynaud's phenomenon and serious hair loss less than patients with systemic lupus erythematosus, anemia, leukopenia, and thrombocytopenia also rare. Procaine amide addition to the drug-induced lupus lesions of the central nervous system there are other drug-induced lupus drugs are rarely involved the central nervous system. Less involvement in the kidney. In laboratory tests, the drug can have lupus patients with systemic lupus erythematosus common ESR by fast, high hypergammaglobulinemia, such as lupus anticoagulant positive. Lupus cells positive rate and systemic lupus erythematosus similar. Drug-induced lupus patients in the pericardial effusion, and pleural effusion often can be found in the cells of lupus. Drug-induced lupus anti-nuclear antibody positive rate of patients with systemic lupus Ferguson, the positive rate of wait, but almost drugs lupus patients there is no anti-double-stranded DNA antibodies and anti-Sm antibodies, and complement level is not reduced, this may be the system SLE with distinction. For lupus drug should be early diagnosis and timely withdrawal. Without special treatment in general, to stop a few days or a few weeks after the lupus symptoms disappeared. Certain drugs and drug-induced lupus patients, the clinical symptoms improved after treatment, but serological abnormalities sustainable for several years. After the withdrawal of a handful of clinical symptoms dissipated, can be used aspirin, indomethacin, ibuprofen and other non-steroidal anti-inflammatory drugs, pay attention to the application of such drugs to prevent the kidney effects. And pericarditis with pleurisy, such as serious illness, may be adequate adrenal hormone therapy. Apart from certain drugs, often in the daily lives of some of aromatic ring and Hydrazine food or cosmetics, as well as certain foods, dyes, tobacco containing amine component of the drug-induced lupus, or do not use should be minimal.