Thursday, March 20, 2008

How diagnosis of lupus nephritis?

The incidence of lupus nephritis forms can be asymptomatic proteinuria / hematuria,: acute glomerulonephritis syndrome, chronic nephritis syndrome, radical type nephritis, nephrotic syndrome, chronic renal insufficiency, and other manifestations. Immunological changes include various anti-DNA antibodies and increased levels of autoantibodies, Decreased serum complement, circulating immune complexes increased. Current diagnosis of lupus nephritis commonly used by American Rheumatism Association (ARA) 1982 revised diagnostic criteria: The following 11 indicators that four or more are, and includes No. 7. (1) of the Ministry of skin erythema flat or higher than the fixed surface erythema. (2) discoid erythema erythema uplift, there keratosis and hair follicle suppository, the old scar lesions were shrinking. (3) Light-sensitive sunlight caused skin allergies. (4) Oral Ulcer oral, nasal or throat painless ulcer. (5) arthritis two or more peripheral, non-erosive arthritis. (6) serositis pleurisy or pericarditis. (7) renal damage persistent proteinuria over 0.5 g/24h or has possession of urine cells. (8) of the abnormal nerve seizures or mental disorders. (9) hematologic abnormalities hemolytic anemia, neutropenia, or thrombocytopenia, random checks 2nd above. (10) immunological abnormalities lupus cells, anti-double-stranded DNA antibodies, anti - Sm antibodies, syphilis or serum test is a more positive. (11) immunofluorescence test titer or similar abnormal, ruled out drugs lupus syndrome.

No comments: