How treatment Henoch - Schonlein Purpura Nephritis? How to judge the prognosis?

Most of Henoch - Schonlein Purpura Nephritis with children tend to have self-limited, Minor symptoms without special treatment. But in the acute phase should pay attention to keeping warm, bed rest, suspended all suspicious allergy drugs and food, to avoid contact with suspicious allergens. If there can be of allergy symptoms (such as chlorpheniramine and diphenhydramine, Astemizole, etc.) symptomatic treatment. Other symptomatic treatment including anti-infection, lower blood pressure and diuretic therapy. Effect of glucocorticoid on joint pain, abdominal pain and gastrointestinal symptoms have some therapeutic effect, the general use of prednisone 1-2 mg kg_1. D_1, can be used 1-2 weeks. Purpura on severe skin test can be used hydride the pine or succinate-hydride test of the treatment. Generally considered the hormone damage to the kidneys no obvious effects can not be changed Henoch - Schonlein Purpura Nephritis course and prognosis, we can not prevent the recurrence purpura. But for a rapidly progressive glomerulonephritis syndrome onset of anaphylactoid purpura nephritis patients, consideration should be given timely use of high-dose methylprednisolone pulse therapy, and to unite anticoagulant and antiplatelet treatment, about half of patients effective treatment. Some people think that the performance of the nephrotic syndrome patients with Henoch - Schonlein Purpura Nephritis to use hormone therapy, although efficacy as primary nephrotic syndrome, but the swelling and reduce proteinuria or have a certain effect. Cell cyclophosphamide, and other poisons, such as the therapeutic effect is not yet sure. Allergic Purple paralysis nephritis Chinese medicine treatment to Blood Circulation, Qingrejiedu dominated. Henoch - Schonlein Purpura Nephritis efficacy and clinical manifestations of the pathological changes of the type and extent of closely related. Minor lesions and better efficacy of acute nephritis, chronic glomerulonephritis type less effective; to pathological changes II, and III treatment effective. While IV, V-treatment difference. Pathological changes in the IV level and above should pay attention to the protection of renal function. Henoch - Schonlein Purpura Nephritis and the prognosis of patients with kidney closely related to the pathological changes. According to incomplete statistics, about 52 percent of patients within a year in the onset can complete remission, 15% are sustainable existence gross hematuria and proteinuria domain (1_3 grams / day), 18% of the patients sustainable presence of microscopic hematuria and microalbuminuria without glomerular filtration rate decrease, and only 5% below the patients in a few years can progress to chronic renal insufficiency. Some of the children were 10 years of follow-up, results showed that 70% -80% of the patients can complete remission, 15% of the patients still continuing kidney lesions, 8% of the renal failure patients, only 1% of the patients died . , Henoch - Schonlein Purpura Nephritis affect the prognosis of the main factors: ① Age: children with a better prognosis, the prognosis of patients with adult onset poor; ② clinical performance: performance for the large number of proteinuria and hypertension associated with poor prognosis; ③ kidney pathological changes: It was more than the statistics of the type IV patients with a 40% can progress to chronic renal insufficiency, and III patients with the following only 3% could progressed to chronic renal insufficiency; and endothelial with subepithelial immune complexes under deposition of patients, more immune complex is confined to the mesangial area, the prognosis worse.