What is polycystic kidney disease

Polycystic kidney disease is renal cortex and medulla in the number of cysts of a genetic kidney disease. According to genetic pattern into two types: (1) autosomal dominant genetic type, This type of general symptoms appeared only to adult; (2) autosomal recessive genetic type, the general performance in the baby that is obvious. Autosomal dominant polycystic kidney Clinical common, accounting for end-stage renal disease 5% --- 10%. Clinical manifestations mainly kidney enlargement, hematuria, proteinuria, hypertension, advanced renal failure can occur. Current treatment of this disease is mainly active control hypertension and complications such as infection control, protection of renal function, delaying the arrival uremia. When there uremia for dialysis treatment and kidney transplantation. Clinical manifestations 1. Lumbar, abdominal discomfort or partially hidden 2. Hematuria (endoscopic or the naked eye), 3. Proteinuria and interleukin urine; 4. Hypertension; 5. Recurrent urinary tract infection, 6. Renal dysfunction, 7. kidney enlargement 8. extra - renal manifestations, including polycystic liver and such as intracranial aneurysms. Diagnosis 1. A conclusive family history of the disease; 2. Imaging examination confirmed that the number of cysts filled with liquid spread on both sides of the kidney cortex and medulla, 3. Gene linkage analysis inspection positive 4. Polycystic liver, brain aneurysms, pancreatic cysts or renal insufficiency can be used for auxiliary basis. Treatment principles 1. Actively seized of complications, such as hypertension, urinary tract infection, obstruction, etc. 2. Cyst large cyst decompression feasible, but be careful; 3. End-stage renal failure can be used for combining traditional Chinese and western medicine treatment, taking " uremic of Hope "series hemodialysis treatment or kidney transplantation. Medication principle to switch to the 5-8 in the C of the 1-2 species; 2. Advanced should be used in patients with severe combined therapy, renal failure and uremia polycystic kidney treatment of non-identical 3. if the cyst excessive bleeding or oppression uncontrollable may consider surgery. Supplementary examination 1. Polycystic kidney patients in the early ad hoc inspections to check the box restrictions "A" main, but the cyst size A failure diagnosis can choose "B" of the 2 or "C" of the 1, 2. On history than long and late complications in patients who check or ad hoc inspections could include restrictions box "A", "B" and "C." Evaluation 1. Cured: symptoms and signs disappeared, the incidence of renal function returned to the former level 2. Turn for the better: ease symptoms and signs, renal stability; 3. Surprised me: symptoms and signs of improvement in renal function deterioration. Experts suggested that Polycystic kidney disease is a genetic disease, diagnosis defined, their relatives should actively conduct the inspections, particularly in patients with brothers and sisters and their children, in order to take all the necessary measures to control early. Clinical treatment is mainly directed against complications, such as infection control, blood pressure control, etc., this is a good prognosis for the key to a serious hematuria, hypertension, chronic renal failure and heart failure, and so should be handled in good time. The surgical treatment, unless there are strong indications, we must carefully.