Tuesday, March 11, 2008
Klebsiella pneumonia
Klebsiellar outlined pneumonia (klebsiellar pneumonia), also known as pneumoniae pneumonia or Friedländer pneumonia. By Klebsiella pneumoniae (klebsiella pneumoniae) induced acute lung inflammation , was particularly prevalent in the elderly, malnutrition, chronic alcoholism, have chronic broncho-pulmonary disease and systemic failure patients. Cause pathogenesis Klebsiella pneumoniae Gram-negative bacteria, often found in the human upper respiratory and gastro-intestinal, When the lower body resistance, they entered through the respiratory tract and lungs caused large-leaf or lobular consolidation Fusion, Ye over more styles. Lesion exudates viscosity and weight, resulting gap leaves fall. Clostridium bacteria, within the alveolar growth and reproduction, cause tissue necrosis, liquefied form single or multiple abscesses. The lesions involved the pleura, pericardium, can cause purulent exudate or effusion. Fibrous tissue hyperplasia lesions active and easy to machine; Cellulose pleural effusion may occur in the early stage of adhesion. Nosocomial infection in sepsis, Klebsiella and Pseudomonas aeruginosa and Sharett chemoheterotroth are important pathogens, the higher the mortality. The disease found in more middle-aged male patient, the rapid onset, fever, cough, sputum volume and chest pain may have cyanosis, short breath, palpitations, About half of patients with chills, the early shock. Clinical manifestations similar serious pneumococcal pneumonia, but was thick purulent sputum volume, sputum, gray green or red color, noticeable, but not all cases are so typical. X-ray shows lung or lobular consolidation, multiple honeycomb lung abscess, leaves space to fall. Klebsiella pneumonia Although bacterial pneumonia accounts for only 2%, but the high fatality rate (about 30%). Elderly and frail patients with acute pneumonia, toxic serious symptoms and there is bloody sputum smears were to be considered this disease. Yet to be confirmed bacteriological examination of sputum, and with Staphylococcus aureus tuberculosis and other Gram-negative bacteria pneumonia caused by the differential phase. Old, neutropenia, bacteremia and the original prognosis of patients with less serious illnesses. Treatment of early use of effective antibiotics is the key to cure. The first amino-glycosides hygiene, such as gentamycin, kanamycin, tobramycin, and amikacin, intramuscular, intravenous drug use or within the lumen. Severe to increase use of cephalosporins as many spores Meng (cefamandole) cefoxitin (cefoxitin), cefotaxime (cefoxitin). Piperacillin (piperacillin), Mezlocillin (mezlocillin) and the amino-glycosides combined, and ofloxacin effect is excellent. In some cases the use of chloramphenicol, tetracycline and sulfamethoxazole - trimethoprim also effective. Have more severe lung injury, chronic cases sometimes OK lobectomy. The body had other diseases and reduce the immunity of patients prone bacteremia. When mixed with other gram-negative bacteria infection, the prognosis was even worse.
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