Thursday, March 20, 2008
Nephrotic syndrome occurs when hyperlipidemia What are the reasons?
Lipid include cholesterol, triglyceride and phospholipids. Plasma lipid and protein in combination, To exist in the form of lipoprotein and transit. There are five categories of lipoprotein, or chylous particulate (CM), very low density lipoprotein (LVDL), low density lipoprotein (LDL), medium-density lipoprotein (1 DL), high density lipoprotein (HDL). Nephrotic syndrome hyperlipidemia occurred when the mechanism is not yet clear, that nephrotic syndrome, hypoproteinemia colloid osmotic pressure caused by the lower and (or) loss of urine within a regulatory factors caused liver on cholesterol, triglyceride and lipoprotein synthesis increased. Furthermore, nephrotic syndrome, lipoprotein lipase activity decreased, resulting in lipid remove obstacles. At the same time, in experimental nephrotic syndrome found dissolved lipid acyl transfer activity to increase, this could be catalytic enzyme acetyl into lysophosphatidylcholine lecithin, elevated serum phospholipids. This led to the nephrotic syndrome hyperlipidemia.
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