Since the 1960s, there has been has been exploring, looking for a diagnosis of systemic lupus erythematosus sensitivity, specificity, but also reflect systemic lupus erythematosus disease diagnostic criteria. At present most widely to the United States Institute of Rheumatology 1982 revised diagnostic criteria for systemic lupus erythematosus, the sensitivity and specificity of diagnosis are around 96%. (1) erythema cheek butterfly; (2) discoid erythema; (3) sunlight allergy; (4) oral ulcer; (5) Non-erosive arthritis; (6) pleurisy, pericarditis; (7) nephritis, proteinuria more than 0.5 grams per day; (8) the nervous system anomalies: convulsions or mental illness; (9) hematologic abnormalities, hemolytic anemia, or less than 4 x109 WBC / liter, or less than 1.5 lymphocytes X109 / liter, or platelets less than 100 x109 / liter. (10) immunological abnormalities, lupus positive cells, anti-double-stranded DNA antibody or anti-Sm antibodies were positive or false positive syphilis test serum; (11) immunofluorescence anti-nuclear antibody positive. In more than 11 standards, with four or four or more, can be diagnosed with systemic lupus erythematosus.
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