Thursday, March 20, 2008

Loss of salt in the differential diagnosis of nephritis

Loss of salt based on the diagnosis of nephritis are:
① have the typical clinical manifestations of disease;
② large intake of salt (1.0 ~ 20 g / day) can alleviate symptoms;
③ deoxy corticosterone treatment ineffective;
④ normal adrenal cortex function tests;
⑤ urinary aldosterone output increase.
This disease and chronic adrenal insufficiency identification is:
(1) Both can be pigmented skin and mucosa, Salt nephritis but lost more uniform distribution, oral and buccal mucosa less affected, and chronic adrenal insufficiency patients pigmentation was particularly prevalent in the compression, wrinkle, scars, and other sites.
(2) of adrenal corticosteroid, the former less effective, the latter effect is good.
(3) adrenal corticosteroid and its metabolites in the urine excretion, the former normal, which has markedly decreased.
(4) normal carbohydrate metabolism former, the latter often have low blood glucose and insulin abnormalities sensitive, and so on.
(5) adrenocortical function test, the former normal, which lowered.
Due to the handling of the two completely different, and this is very much related with the prognosis, so the differential between importance.

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