Pulmonary aspergillosis

Pathology and pathogenesis of pulmonary aspergillosis (pulmonary aspergillosis) by Aspergillus fumigatus (Aspergillus fumigatus) lead. Parasitic strain in the upper respiratory tract only in patients with chronic lowered immunity can be pathogenic. Air everywhere aspergillosis spores, and rain in the autumn and winter seasons, when the stored heat rotten straw when more. Aspergillosis inhaled spores does not necessarily illness, a large number of inhalation can cause acute tracheal - bronchitis or pneumonia. The disease often has been secondary to lung diseases such as bronchogenic cyst, bronchiectasis, pneumonia, lung abscess, and so on. Aspergillosis of endotoxin make tissue necrosis, lesions of the invasion, it changed, or bronchial periimplantitis miliary Artemis chronic change. Clinical clinical manifestations are four types. A broncho-pneumonia-type aspergillosis in the bronchial mucosa mycelium grown, but not penetrated the wall. Minor mucosal inflammation, cough, sputum (phlegm can brownish yellow), and other low heat. If erosion lung tissue, may cause limitations of aspergillus granuloma or pneumonia, lung abscess. 2, allergic aspergillosis right allergic aspergillosis were a large number of spores inhaled, small bronchial obstruction, cause temporary atelectasis, also can cause a relapse of distal pulmonary infiltration migrans. Patients with chills, fever, fatigue, irritating cough, cough brown evenly, and sometimes bloody. A large number of sputum eosinophils and Qu mycelium. Aspergillus fumigatus culture positive. Patients with significant asthma, blood eosinophilia. 3, aspergilloma parasitic aspergillosis in chronic lung diseases associated with the cavity (such as lung cysts, bronchiectasis, Tuberculosis empty), breeding, storage, and fibrin and mucosa 0530 aspergillosis ball, X-ray visible in the original chronic empty within a video signal regiment, with postural changes in the air cavity Mobile. Aspergillosis balls with violations, not cause systemic symptoms of the patients, only irritating cough, hemoptysis can sometimes repeatedly. As aspergilloma and bronchial more disconnected, the little phlegm, sputum often found no aspergillosis. 4, secondary pulmonary aspergillosis in seriously ill patients (eg, leukemia, lymphoma) the terminal stage, and the use of broad-spectrum antibiotics, Immunosuppressive drugs or various causes low immunity, accompanied by pulmonary aspergillosis infection is widespread limitations pyogenic granuloma or pneumonia, with abscess formation. Lesions showed acute coagulative necrosis, with necrotizing vasculitis, thrombosis and bacteria suppository, or even broadcast and pleural, brain, liver, spleen of all the organs, the prognosis is poor. Diagnosis of pulmonary aspergillosis diagnosis of the disease occupational history, clinical manifestations and X-ray examination, the diagnosis relies on the training and histological examination. Repeatedly smear or bronchoscopy brushing sampling, see hyphae and diameter of about 2-3um circular brown or dark green spores, as the top enlargement chrysanthemum-shaped. Training of grayish green buds Health colony, who are microscopic examination confirmed spores and the spores into a chain. Allergic-type who can also be found in sputum lot of eosinophils. Aspergillosis leaching solution used for antigen skin test, the patients have allergic-type reaction speed hairstyle, suggesting a IgE antibody. Serum precipitation test (IgE antibodies exist, the type III allergic), or agar diffusion test diagnosis of the disease will also help. For the treatment of septic pneumonia and blood broadcast aspergillosis also uses amphotericin B, also available fluorocytosine or hydroxyl Effects of Pakistan amidine (hydroxystilbamidin). Allergic-type aspergillosis can be added glucocorticoids, bronchial spasm agent. Aspergilloma lesions confined to a large number of recurring hemoptysis were feasible surgical resection, because of poor antifungal effect.