Anticoagulant treatment of acute myocardial infarction

Acute myocardial infarction early anticoagulant and platelet inhibitor for the purpose of: ① early prevention of further expanding area of infarction or infarction, to reduce mortality; ② ventricular wall to prevent arterial thrombosis and embolism occurred; ③ prevention of deep vein thrombosis and pulmonary embolism ; ④ late to prevent the re-infarction myocardial infarction and death. In general, for all did not receive thrombolytic therapy in patients with severe acute myocardial infarction patients without contraindications, the hospital can give subcutaneous injection of heparin calcium 50 ~ 75 mg (5000 ~ 7500IU) once every 12 hours or intravenous heparin 5000 IU And then continuous infusion 600 ~ 800 IU / hour, three to five days. Clotting time to keep control of 1 to 1.5 times. At the same time oral low-dose aspirin 160 mg / day, who can be tolerated in patients with long-term aspirin use. The anterior myocardial infarction, echocardiography found mural thrombosis, should switch to long-term oral warfarin. Thrombolytic therapy in patients, the use of thrombolytic agents different from the beginning of anticoagulant treatment difference in time. For intravenous infusion tPA because of its short half-life of the application at the same time the immediate use of anticoagulant heparin. The use of urokinase or streptokinase, often in question after the infusion of drug or ACT PTT returned to 2 times the value of control, fibrinogen restored to more than 100 mg / ml application. For a bleeding tendency, activities of the ulcer, history of cerebral hemorrhage, blood pressure higher than the 24/14 7kPa (180/110mmHg), a serious liver and kidney diseases and cancer patients, and so should Jiyong.