Myocardial infarction and excessive fatigue, emotional volatility

Just a 45-year-old colleague has just come from the grass-roots hospitals in the hospital, because of the pressure of life, such as plague and housing, psychological and spiritual pressures. It was in prior to the onset of another cut on the eve of the examination, Aoye continuous learning, make it more tension fatigue. At the end of the day due to myocardial infarction single family died. Excessive fatigue, excessive physical activity or emotional stress can trigger myocardial infarction, probably due to activation of the sympathetic nervous system, cause high blood pressure and hemodynamics, such as tachycardia, while sympathetic activation system can cause coronary artery spasm contraction , An increase of platelet aggregation, dissolution of lower fiber, reduce the release of prostaglandin, easily formed thrombosis. Plaque rupture easily, so that the collagen plaque, atherosclerosis nuclear components exposed to the coronary blood flow, leading to formation of thrombus emboli. If thrombosis is not completely blocked coronary blood flow, clinical performance, for unstable angina or non-Q wave myocardial infarction, if completely blocked coronary artery thrombosis, is not sufficient collateral circulation in the circumstances, the occurrence of acute myocardial infarction . Certain factors alone can not trigger-induced myocardial infarction infarction, but many factors mutual synergies could lead to thrombosis. For example, smokers are accustomed to the sedentary (contraction of the coronary artery to increase, high blood coagulation status) re physical activity, can be induced plaque rupture. However, the existence of extremely vulnerable plaques in patients, even in daily life without tension, still able to trigger cardiovascular events. Substantial evidence that patients with acute myocardial infarction and Sudden cardiac death is a "trigger event", in a cyclical, seasonal changes and non-randomness. Many studies on the plaque internal and external factors triggering factor in the atherosclerotic plaque rupture of the important role of the assessment, found that about 20 percent of the non-fatal myocardial infarction and trigger factors are closely related. Another study showed that in all cardiovascular events, about one-third of the incident have a clear trigger factors to trigger another one-third of the incident (such as psychological factors), as too delicate and difficult from the limited Identified in the history of information; the remaining one-third of the incident, was due to internal factors caused by plaque. Myocardial infarction and Sudden cardiac death is obvious, cyclical changes in the morning wake up, get up after the increased risk of cardiovascular events, which may originate from Chen Qi after the physical and mental activities increased due to factors such as trigger. However, cardiovascular events of the day may have other time, despite its relatively low incidence rate. External trigger factors and myocardial infarction, the incidence of Sudden cardiac death is closely related. Understanding of external factors to trigger cardiovascular events and the causal relationship to improve the prognosis of patients with significant.