Wednesday, June 18, 2008
Why chronic renal failure patients with heart failure
Heart failure is the CRF important cause of death and serious complications, CRF of heart failure is the result of many factors, including: (1) excessive blood volume: CRF, increased blood volume, left ventricular end-diastolic capacity, the volume of stroke and cardiac output increase, beware compensatory function can not be there when you left ventricular dysfunction and lead to heart failure. (2) Hypertension: long-term hypertension to heart overloading, caused heart wall hypertrophy, heart expand, the long-standing cause heart failure. Uremic plasma catecholamine concentrations increased, with its higher degree of heart failure is closely related. In addition, because of high blood pressure and accelerated atherosclerosis in progress to a heart failure. (3) the role of uremic toxins: CRF when the accumulation of harmful metabolites in the body, toxins inhibit myocardial caused cardiomyopathy, leading to cardiac dysfunction and heart failure. (4) electrolyte metabolic disorder and acid poisoning: CRF due to cardiac, electrolyte imbalance and cardiac excitability change, leading to arrhythmia and heart failure. (5) renal anemia: CRF patients with long-term anemia to myocardial ischemia, myocardial dysfunction. As the body decompensated heart rate to accelerate, increase cardiac output, falling into the heart due to overloading, myocardial ischemia can lead to heart failure. (6) dialysis arteriovenous fistula: because of the dynamic blood flow, increase the heart load, can lead to a long-standing heart failure. (7) atherosclerosis: CRF with high blood pressure and dialysis after the hyperlipidemia, can be accelerated atherosclerosis in progress, so that the mortality rate increased CRF, in the process of dialysis are often a result of myocardial infarction and death. (8) immunocompromised: uremia at the lower-immunity from infection and infection caused myocarditis or pericarditis leading to heart failure.
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