In clinical acute renal failure What are the risk factors

Acute renal failure (ARF) are common, involving internal and external, UNIFEM, UNICEF, transmission and trauma, and other disciplines. ARF often before there are certain risk factors, with these risk factors may be known as the ARF are Yizhi the high-risk groups, attention to these risk factors, be properly handled, can prevent the occurrence of ARF. These risk factors are: ① the elderly and child care: the elderly kidney function degradation, drug detoxification and the reduced ability of the sensitivity of renal toxicity of drugs, vulnerable to ARF. Child care easier, there dehydration, low blood pressure, such as the shortage of blood volume; ② low blood volume: a variety of reasons caused by bleeding, kidney and gastrointestinal fluid loss, loss of skin liquid (such as burns, excessive sweating), a lack of blood volume. Low blood volume, reduce kidney blood flow, GFR decline, while sympathetic excitement and vasopressin increased from renal vasoconstriction, GFR decline further, and induce ARF; ③ cycle of dysfunction: a variety of reasons arising from the shock, heart failure, and other cycle dysfunction, caused by lack of renal perfusion, GFR decline. Excessive use of antihypertensive drug-induced is also a factor; ④ serious infection and sepsis: serious infections, particularly those with sepsis by kidney and renal toxicity mechanism of ischemia induced by ARF; ⑤ severe trauma: such as burns, crush injury, fractures and other serious because of shock, infection and trauma organizations release of myoglobin, and so prone to ARF. Severe burns, massive loss of liquid and intravascular hemolysis also vulnerable to ARF; (6) after surgery: the incidence of serious, narcotic and sedative drug use, tissue trauma, loss of, so that factors such as surgical blood loss after major surgery-prone ARF. Renal failure after heart surgery depends on the opportunities and cardiopulmonary short time after the restoration of heart function; ⑦ obstetric complications: early pregnancy abortion pollution rhyme: Advanced serious pregnant while in high, bleeding, pain and other complications of both easy-induced ARF; ⑧ cirrhosis and ascites: At this point plasma renin - Zhang renal-vascular - aldosterone system has been activated, such as vasopressin lead to increased secretion of kidney Shuinazhuliu. Liver dysfunction drug detoxification ability. At this point if ascites put too much too fast can easily induce ARF, the use of renal toxicity of these patients also vulnerable to drug ARF; ⑨ renal toxicity of drugs: the use of renal toxicity of drugs such as aminoglycoside drugs, imaging agents and cephalosporins, particularly in the elderly, child care, dehydration, diabetes, cirrhosis, kidney disease who have particular application Dangerous and easy to induce ARF; ⑩ kidney diseases: chronic kidney disease can often affect the self-regulatory function of the kidney, the disease can exacerbate or some additional factors (infections, urinary tract obstruction, water electrolyte imbalance, kidney toxicity induced by drug use and ARF . Nephrotic syndrome associated with idiopathic acute renal failure in recent years, attention can be effective because of insufficient blood volume cycle, the type of tubular obstruction, renal interstitial edema and renal tubular oppression vein thrombosis, and other mechanisms to enable integrated nephropathy Levy in ARF, that kidney disease should be regarded as an independent risk factor. In addition, the use of older BPH anticholinergic drugs, renal hypertension use of angiotensin-converting enzyme inhibitors, abuse of non-steroidal anti-inflammatory Drug, cyclosporin and excessive chemotherapy drug-induced acute hyperuricemia, and so on are easily induced ARF.